Running for exercise appears to lower inflammation in the knees, not aggravate it, according to a new study. Researchers measured levels of pro-inflammatory molecules in the knee-joint fluid of a group of men and women before and after 30 minutes of running, and they found that levels of two such molecules decreased. While this study focused on relatively young, healthy people, other research has linked running to a decreased risk of developing osteoarthritis in people of all ages. Exercise is essential for those who have osteoarthritis too — but running may or may not be the best bet. If you've been diagnosed with arthritis or have joint pain, work with your physician or a physical therapist to come up with a fitness plan. If your joints are fine but you don't enjoy running, there are many other forms of exercise that benefit not just your joints but also your bones, muscles, heart, and brain. Whether you prefer to walk briskly, swim, hike, bike, or dance the night away…just do it. If you've been sedentary, work up to about 30 minutes of walking most days of the week.
Source: Running Decreases Knee Intra-Articular Cytokine and Cartilage Oligomeric Matrix Concentrations: A Pilot Study
“In most cases, exercise does more good than harm to joints.” Professor Patrick McNeil